Escin (Aescin) is acquired from the seeds of the horse chestnut tree, which originated from Asia and was aboriginal alien in
Escin is a saponin begin in horse chestnuts, the seeds of the horse chestnut tree, as able-bodied as in added bulb species.
Escin exists in two forms, alfa and beta, which can be differentiated by their melting point, their specific rotation, their haemolytic activity and their solubility in water. The beta anatomy of escin is the alive basic in horse chestnut extract. Three types of pharmacodynamic activity accept been attributed to escin: anti-oedematous properties, anti-inflammatory activities and phlebotonic properties.
Escin is commonly acclimated in the appropriate analysis of anatomic disorders of cutaneous capillary airiness such as ecchymoses, petechia, venous dearth (heavy legs) and in the symptomatology of haemorroidal crisis.
The pharmacopoeia about accepts the use of horse chestnut (titrated Escin abstract at 16-20%) in dissection manifestations of abiding venous dearth (pain, heaviness, cramp, oedemas and itching). Escin is acclimated in the agreement biologic specialities in contemporary gels (Phlebogel, Aesculaforce).
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