PON1 Function

PON1 is amenable for hydrolysing organophosphate pesticides and assumption gasses. Polymorphisms in the PON1 gene decidedly affect the catalytic adeptness of the enzyme.

PON1 (paraoxonase 1) is aswell a above anti-atherosclerotic basic of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-γ, which increases amalgam and absolution of paraoxonase 1 agitator from the liver, abbreviation atherosclerosis.